CEInfinite Automated Preparative iCIEF System
In response to the tremendous and urgent need for the identification of protein charge variants, Advanced Electrophoresis Solutions Ltd. has developed the CEInfinite Automated Preparative iCIEF instrument system.
Why choose CEInfinite?
Minumum R&D from iCIEF platform method.
A fully automated system allows ~100ug fraction per day.
Capillary Diameter Transfer Techonology
Our proprietary capillary diameter transfer technology (CDTT*) allows the high resolution preparation of charge variant isomers. Once the proteins are focused, the mobilization process begins and the peaks are pushed out of transfer capillary. This is visualized in real time on-screen via the whole column image detection (WCID) of iCIEF, which is not present in single-point detection CIEF.
During mobilization, the electric field is still applied to the separation capillary and the CDTT maintains the separation resolution of the sample into the narrower transfer capillary for high purity fractions of low pI different isomers.
*US Patent 10935519
|Detection mode||Whole column, sCMOS imaging technology|
|Sample capacity||84+3 vial tray, 96 well plate|
|Sample tray temperature||4 - 40°C|
|Detection dynamic range||250 (0.004 – 1.0AU, 280nm)|
|High voltage range||0 – 3000volts (Continuously Adjustable)|
|Sample throughput||Up to 12 injections per hour|
|Working temperature||15 - 35°C|
|Humidity||20 - 80%RH|
|Electrical requirement||100/240VAC, 50 - 60Hz|
|Exposure time||0.02 – 99.9ms|
|Operation mode||Manual or automatic|
|Detector noise||Less than 0.001AU, 280nm|
|Separation pH range||2.1 – 11.1|